Prof. Evan Elliott


    List of Publications (reverse order)

    1. Atlas R, Behar L, Elliott E, Ginzburg I (2004) The insulin-like growth factor mRNA

    binding-protein IMP-1 and the Ras-regulatory protein G3BP associate with tau mRNA and HuD protein in differentiated P19 neuronal cells. Journal of Neurochemistry. 89:613-626.

    1. Elliott E, Atlas R, Lange A, Ginzburg I (2005) Brain-derived neurotrophic factor

    induces a rapid dephosphorylation of tau protein through a PI-3 Kinase signalling mechanism. European Journal of Neuroscience 22:1081-1089.

    1. Elliott E, Ginzburg I (2006) The role of neurotrophins and insulin on tau pathology in Alzheimer's disease. Reviews in the Neurosciences. 17:635-642.


    1. Elliott E, Tsetkov P, Ginzburg I (2007) BAG-1 associates with Hsc70/tau

    complex and regulates the proteasomal degradation of tau protein. Journal of Biological Chemistry. 282(51): 37276-84.

    1. Blumenthal J, Behar L, Elliott E, Ginzburg I (2009) Dcp1a phosphorylation along    

    neuronal development and stress.  FEBS Letters. 583(1):197-201.

    1. Elliott E, Ginzburg I (2009) BAG-1 is preferentially expressed in neuronal

    precursor cells in adult mice and mediates cellular proliferation.  FEBS Letters. 583(1):229-34.

    1. Elliott E, Laufer O, Ginzburg I (2009) BAG-1M is upregulated in Alzheimer's

    Disease patients and associates with APP and tau proteins. Journal of Neurochemistry. 109(4):1168-1178

    1. Elliott E, Ezra G, Regev L, Neufeld-Cohen A, Chen A (2010) Resilience to social stress coincides with functional DNA methylation of the CRF gene in adult mice.

    Nature Neuroscience. 13: 1351-1353

    1. Tsvetkov P, Adamovich Y, Elliott E, Shaul Y. (2011) E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients. Journal of Biological Chemistry. 286(11):8839-45


    1. Sterrenburg L, Gaszner B, Boerrigter J, Santbergen L, Bramini M, Elliott E, Chen A, Peeters BW, Roubos EW, Kozisc T (2011) Chronic Stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat. Plos One. 6(11):e28128


    1. Nardone S, Sams D, Reuveni E, Getselter D, Oron O, Karpuj M, Elliott E (2014) DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways. Translational Psychiatry. 4:e433.


    1. Mor M, Nardone S, Sams D, Elliott E (2015) Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex. Molecular Autism. 6:46. 


    1. Kratsman N, Getselter D, Elliott E (2016) Sodium Butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. Neuropharmacology. 102:136-45.


    1. Elliott E, Manashirov S, Zwang R, Gil S, Tsoory M, Chen A (2016) DNMT3a in the medial prefrontal cortex regulates anxiety-like behavior in adult mice. Journal of Neuroscience. 36(3):730-40.


    1. Nardone S, Elliott E (2016) The interaction between the immune system and epigenetics in the etiology of autism spectrum disorders. Frontiers in Neuroscience. 10:329. 


    1. Shemesh Y, Forkosh O, Mahn M, Anpilov S, Sztainberg Y, Manashirov S, Shlapobersky T, Elliott E, Tabouy L, Ezra G, Samantha Adler E, Ben-Efraim Y, Gil S, Kuperman Y, Haramati S, Dine J, Eder M, Deussing JM, Yizhar O, Schneidman E, Chen A (2016) Ucn3–CRFR2 in the medial amygdala regulates socio-emotional balance in mice. Nature Neuroscience. 19(11):1489-1496. 


    1. Sams DS, Nardone S, Getselter D, Raz, D, Tal M, Rayi PR, Kaphzan H, Hakim O, Elliott E (2016) Neuronal CTCF is necessary for basal and experience-dependant gene regulation, memory formation and genomic structure of BDNF and Arc. Cell Reports. 22 17(9):2418-2430


    1. Oron O, Elliott E (2017) Delineating the common biological pathways perturbed by ASD’s genetic etiology: lessons from network-based studies. International Journal of Molecular Sciences. 18(4):828


    1. Nardone S, Sam D, Reuveni E, Elliott E (2017) Dyregulation of cortical neuron DNA methylation in autism spectrum disorders. Cerebral Cortex. 27(12):5739-5754.


    1. Davis L, Onn I, Elliott E (2018) The emerging roles for the chromatin structure regulators CTCF and cohesin in neurodevelopment and behavior. Cellular and Molecular Life Sciences. (7):1205-1214.


    1.  Reuveni E, Getselter D, Oron O, Elliott E (2018) Differential contribution of cis and 

    trans gene transcription regulatory mechanisms in amygdala and prefrontal  cortex and   modulation by social stress. Scientific Reports. 8(1):6339

    1. Tabouy L, Getselter D, Weber N, Ziv O, Koren O, Elliott E. (2018) Dysregulation of

    microbiome and effects of probiotic treatment in genetic autism mouse model.         Brain Behavior and Immunology. S0889-1591(18)30188-0


    1. Polis B, Srikanth KD, Elliott E, Gil-Henn H, Samson AO. L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease (2018). Neurotherapeutics. Oct;15(4):1036-1054.


    1. Lukic I, Getselter D, Ziv O, Oron O, Reuveni E, Koren O, Elliott E.  (2019)

    Antidepressants affect gut microbiota and Ruminococcus flavefaciens is able to abolish their effects of depressive-like behavior. Translational Psychiatry.  9(1):133


    1. Werbner M, Barsheshet Y, Werbner N, Zigdon M, Averbuch I, Ziv O, Brant B, Elliott E, Gelberg S, Titelbaum M, Koren O, Avni O. (2019) Social-Stress-Responsive Microbiota Induces Stimulation of Self-Reactive Effector T Helper Cells. mSystems. 2019 May 14;4(4)


    1. Lukić I, Getselter D, Koren O, Elliott E. (2019). Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study. Front Behav Neurosci. 2019 Jun 4;13:123.


    1. Oron O, Getselter D, Shohat S, Reuveni E, Lukic I, Shifman S, Elliott E. Impaired Risk assessment behavior is associated with dysregulated striatal glutaminergic signaling in autism mouse models. Translational Psychiatry. 2019 Oct 17;9(1):257



    1. Palmisano I, Danzi MC, Hutson TH, Zhou L, McLachlan E, Serger E, Shkura K, Srivastava PK, Hervera A, Neill NO, Liu T, Dhrif H, Wang Z, Kubat M, Wuchty S, Merkenschlager M, Levi L, Elliott E, Bixby JL, Lemmon VP, Di Giovanni S. (2019) Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons. Nature Neuroscience. 2019 Nov 22(11):1913-1924.


    1. Frankiensztain LM, Elliott E, Koren O. The microbiota and the hypothalamus-pituitary-adrenocortical (HPA) axis, implications for anxiety and stress disorders. Current Opinion in Neurobiology. 2020. Jun 62:76-82


    1. Perets N, Oron O, Herman S, Elliott E, Offen D. Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B. Mol Autism. 2020 Aug 17;11(1):65.


    1. Aviel-Shekler K, Hamshawi Y, Sirhan W, Getselter D, Srikanth KD, Malka A, Piran R, Elliott E. Gestational diabetes induces behavioral and brain gene transcription dysregulation in adult offspring. Translational Psychiatry. 2020. Nov 25:10(1):412
    2. Fonar G, Polis B, Sams DS, Levi A, Malka A, Bal N, Maltsev A, Elliott E, Samson AO. Modified Snake alpha-neurotoxin averts beta-amyloid binding to alpha7 Nicotinic Acetylcholine Receptor and Reverses Cognitive Deficits in Alzheimer’s Disease Mice. Molecular Neurobiology.  2021. May 58(5): 2322-2341
    3. Weissberg O, Elliott E. The mechanisms of CHD8 in Neurodevelopment and Autism Spectrum Disorders. Genes. 2021. July 26;12(8):1133
    4. Davis L, Rayi PR, Getselter D, Kaphzan H, Elliott E. CTCF in parvalbumin-expressing neurons regulates motor, anxiety and social behavior and neuronal identity. Molecular Brain. 2022. April 4

    Last Updated Date : 03/11/2022